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Studies evaluating performance measures of pan-enteric capsule endoscopy (PCE) exams are scarce. The authors aimed to assess PCE studies from a tertiary centre and to identify predictive factors for incomplete procedures and poor bowel cleanliness.

MethodsA retrospective analysis of all consecutive PCE studies performed in a tertiary centre between March 2018 and January 2022 was conducted. All patients were given the same bowel cleansing procedure. The authors evaluated completeness of the procedure, adequate small-bowel (SB) cleanliness and adequate colon cleanliness. Statistical analysis to identify predictors of incompleteness of the procedure and inadequate bowel cleanliness was performed, concerning several demographic, disease-related, medications and patient status factors, using univariate and multivariate binary logistic regression analyses. ResultsEighty PCE procedures were included in this study, 56.3% of which were from female patients. Median age of the patients was 40 (IQR 24) years. Only one patient had inadequate SB cleansing, thus statistical analysis of this outcome was not undertaken. 55 (68.8%) patients had adequate colon cleanliness and 55 (68.8%) of the procedures were complete. On univariate analysis, inability to walk without assistance, inpatient status, cardiac disease, diabetes, dyslipidemia, neurodegenerative disease, previous abdominal surgery, beta-blocker use and higher Charlson Comorbidity Index were predictors of poor colon cleanliness. On multivariate analysis, however, no independent predictors of poor colon cleanliness were identified. Concerning incompleteness of the procedure, the following factors were predictors of this outcome: inpatient status, advanced age and cardiac disease. On multivariate analysis, inpatient status was the only independent predictor of this outcome (HR = 11.1; 95% CI 1.1– 117.3; p=0.04).DiscussionAlthough the authors found several predictive factors of poor colon cleanliness, no independent predictive factors of this outcome were identified. Inpatient status was an independent predictor of incompleteness of the procedure, thus calling for appropriate pre-emptive measures in this patient population.

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